Seminar
Laser Transmission Spectroscopy
Steven T. Ruggiero, Department of Physics, University of Notre Dame
Friday, March 11, 2011, 2:00 pm Mountain Time
DSRC 2A305
Abstract
Laser Transmission Spectroscopy (LTS) is a new and powerful platform for nanoparticle characterization. It is unique in providing the diameter, shape (length and width of rod-shaped objects), and density of nanoparticles in solution over the size range of 5 to 3000 nanometers. It has a maximum sensitivity of ~ 1000 objects/mL and a size resolution of 2-3 nm. This is far higher sensitivity and resolution than dynamic light scattering, as we have shown by direct comparisons. I will discuss the fundamentals and performance of LTS and its many applications including the characterization of nanoparticles and pathogens in the environment, species-specific DNA detection, protein analysis, and its potential for medical diagnostics.
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